85-2060-18　Ganglioside GD1a, Disodium Salt 1mg　CAS No:12707-58-3　207198

特徴

• Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GD1a is the major ganglioside of the nervous system. It is converted to GM1 by bacterial, viral and mammalian sialidases. It is a differentiation marker for cell growth.
• Synonyms:12707-58-3
• Source:Bovine brain
• Molecular Formula:C84H146N4O39.2Na
• Molecular Weight:~1836.1, 46.0 (calculated on sphingosine C18:1 and stearic acid)
• Appearance:Supplied as a lyophilized powder.
• Purity:≥98% (TLC)
• Method for Determining Identity:Proton NMR, MS and HPTLC.
• Solubility:Soluble in H2O (micellar aggregates) or chloroform:methanol (2:1)
• Storage and Stability:Store at -20°C for long term storage. Hygroscopic. Protect from moisture. For maximum recovery of product, centrifuge the original vial prior to removing the cap.