85-2059-79　FasL, Soluble, Recombinant, Human, aa139-281 (Apoptosis Antigen Ligand, APT1LG1, APTL, CD95 Ligand, CD95L, CD95-L, FAS Antigen Ligand, Fas Ligand, CD178, FASLG, Tumor Necrosis Factor Ligand Superfamily Member 6, TNFSF6) 10ug　207170

特徴

• Fc (human):FasL, Soluble (human) is a high activity construct in which two trimeric FasL are artificially linked via the Fc binding domain of human IgG1. This construct very effectively simulates the natural membrane-assisted aggregation of FasL in vivo. FasL is a cytokine that binds to TNFRSF6/Fas, a receptor that transduces the apoptotic signal into cells. It is involved in cytotoxic T cell mediated apoptosis and in T cell development.
• Source:Recombinant protein corresponding to aa139-281 from human FasL, fused at the N-terminal to the Fc portion of human IgG1, expressed in HEK 293 cells.
• Molecular Weight:~50kD (SDS-PAGE)
• Biological Activity:Induces apoptosis of human Jurkat T cells at a concentration of <0.2ng/ml.
• Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.