85-2059-67　Echinomycin (Quinomycin A) 1mg　CAS No:512-64-1　207159

特徴

• Antibiotic. Antitumor compound. Powerful, selective inhibitor of nucleic acid synthesis in vitro. Potent hypoxia-inducible factor 1 (HIF-1) DNA binding activity inhibitor. Apoptosis inducer. Antibacterial, antifungal and antiviral.
• Alternate Names:Echinomycin, Actinoleukin, Antibiotic 1491, Antibiotic 59266, Antibiotic X 948, Antibiotic X 53III; N-(2-Quinoxalinylcarbonyl)-O-[N-(2-quinoxalinylcarbonyl)-D-seryl-L-alanyl-3-mercapto-N,S-dimethylcysteinyl-N-methyl-L-valyl]-D-seryl-L-alanyl-N-methylcysteinyl-N-methyl L-valine (81)-lactone cyclic (37)-thioester
• Source:Streptomyces echinatus (DSM 40013)
• Molecular Formula:C51H64N12O12S2
• Solubility:Acetone, DMSO (50mg/ml), methanol, dichloromethane or ethyl acetate.
• Method for Determining Identity:Proton NMR
• Molecular Weight:1101.3
• Appearance:Supplied as a white to off-white solid.
• Purity:≥98% (HPLC)
• Storage and Stability:Store at -20°C under inert atmosphere. Hygroscopic. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
• Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.