Potent and selective protein phosphatase 2A (PP2A) inhibitor. Cell adhesion inhibitor. Inhibits the adhesion of B16 melanoma cells to laminin and collagen type IV in a dose dependent manner but not to fibronectin. Antitumor agent. Antimetastatic. Apoptosis inducer.
Source:Streptomyces sp. MJ654-NF4
Formula:C21H32NaO7P
Solubility:Methanol, chloroform, ethyl acetate, DMSO or H2O
Molecular Weight:450.4
Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size:250ug
Source Antigen:Streptomyces sp. MJ654-NF4
Grade:Purified
Purity:≥75% (HPLC)
Form:Supplied as a yellowish powder.
Molecular Formula:C21H32NaO7P
Molecular Weight Non Ab:450.4
EU Commodity Code:38220090
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CAS No :156856-30-3,457070-06-3, 682329-63-1(free base)