85-2058-87　Bafilomycin A1 (NSC381866) 100ug　CAS No:88899-55-2　207083

特徴

• Bafilomycin A1 is a member of a potent family of macrocyclic lactones with a broad spectrum of biological activity including activity against bacteria, yeast, fungi, nematodes, insects and antitumor cell lines. Bafilomycin A1 is an inhibitor of vacuolar-type ATPase. Related to: Bafilomycin B1, Bafilomycin C1, Concanamycin A.
• Source:Streptomyces griseus
• Synonyms:21-O-De(3-carboxy-1-oxo-2-propenyl)-2-demethyl-2-methoxy-24-methyl-hygrolidin Oxacyclohexadecane, hygrolidin deriv.; (-)-Bafilomycin A1; NSC 381866; [7R-[3Z,5E,7R*,8S*,9S*,11E,13E,15S*,16R*[1S*,2R*,3S*(2R*,4R*,5S*,6R*)]]]-8-Hydroxy-16-[2-hydroxy-1-methyl-3-[tetrahydro-2,4-dihydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]butyl]-3,15-dimethoxy-5,7,9,11-tetramethyl-oxacyclohexadeca-3,5,11,13-tetraen-2-one
• Molecular Formula:C35H58O9
• Molecular Weight:622.8
• Purity (HPLC):≥98%
• Appearance:Supplied as an off-white solid
• Solubility:Soluble in DMSO, 100% ethanol or methanol
• Method for Determining Identity:Proton NMR Spectroscopic Analysis
• Storage and Stability:May be stored at 4ºC for short-term only. Long-term storage is recommended at -20°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Vortex before use.
• Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
• Toxicity and Hazards:All products should be handled by qualified personnel only, trained in laboratory procedures.