Human secreted Programmed Cell Death 1 Ligand 1 (PD-L1)-Fc fusion protein, also known as CD274 and B7 homolog 1 (B7-H1), GenBank Accession No. NM_014143, amino acids 19-239, with C-terminal expressed in a HEK293 cell expression system and enzymatically biotin-labeled. MW = 54kD.
Source:Recombinant protein corresponding to aa19-239 of PD-L1 at the C-Terminus, expressed in a HEK293 cell expression system.
Molecular Weight:~54kD
Application:Useful for the study of enzyme kinetics, screening inhibitors, and selectively profiling.
Storage and Stability:Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Amino Acid Sequence:(19) FTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPYNKINQRILVVDPVTSEHELTCQAEGYPKAEVIWTSSDHQVLSGKTTTTNSKREEKLFNVTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIPELPLAHPPNERT (239)DIEGRMD (Linker)100PKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGVFSCSVMHEALHNHYTQKSLSLSPGK (330) Fc of human IgG1GGGLNDIFEAQKIEWHE (Avi-tagTM)
仕様
Source Antigen:Recombinant, HEK293
Grade:Highly Purified
Purity:~90%
Form:Supplied as a liquid in 40mM Tris-HCl, pH 8.0, 110mM NaCl, 2.2mM KCl, 20% glycerol. Labeled with Biotin.