Tetrahydrocortisol is excreted in large amounts in premenopausal patients with early breast cancer. Tetrahydrocortisol has been found to be produced by lymphocytes in both normal and cancer bearing patients however, the concentration of Tetrahydrocortisol has increased in patients with cancer.
Melting Point:200-203ºC
Solubility:Chloroform (sparingly), Methanol
Method for Determining Identity:Proton (CDCl3) NMR Spectroscopic and Mass Spectrometric Analysis
TLC Conditions:SiO2; Dichloromethane: Methanol=9:1; Visualized with KMnO4; (Single spot, Rf=0.35)
Storage and Stability:Store at -20°C under an atmosphere of inert gas. Stable for 6 months after receipt. Caution: Hygroscopic. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
