Desfluoro Atorvastatin is an impurity in the synthesis of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
Alternate Name:(βR,δR)-β,δ-Dihydroxy-2-(1-methylethyl)-4,5-diphenyl-3-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Calcium Salt (2:1)
Impurity:Atorvastatin Related Compound A
Appearance:Supplied as a white solid.
Molecular Formula:C₆₆H₆₈CaN₄O₁₀
Molecular Weight:1119.36
Melting Point:>193°C (dec.)
Solubility:DMSO, Methanol
Storage and Stability:Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
