Isotope labelled Caspofungin Acetate, an echinocandin that inhibits the synthesis of β (1,3)-D-glucan, an integral component of the fungal cell wall. An antifungal drug used in the treatment of invasive fungal infections.
Synonyms:1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-(threo-3-hydroxy-L-ornithine)pneumocandin B0 Diacetate-d4; Cancidas-d4; Caspofungin Diacetate-d4; L 743872-d4; L 743873-d4; MK 0991-d4; 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]pneumocandin B0 Diacetate-d4
Molecular Formula:C₅₆H₉₂D₄N₁₀O₁₉
Molecular Weight:1217.44
Appearance:Supplied as a white to off-white solid.
Purity:Chemical: 95% Isotopic: 98%
Melting Point:>117°C (dec.)
Atmosphere:Inert Gas
Solubility:Methanol (Slightly), Water (Slightly, Heated)
Method for Determining Identity:Proton NMR (CD3OD) Spectroscopic and Mass Spectrometric Analysis
TLC Conditions:C18; Methanol: Water :Acetic Acid= 8:2:1; Visualized with AMCS; Single Spot, Rf=0.30
Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at -20°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Store under inert atmosphere.
Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards:All products should be handled by qualified personnel only, trained in laboratory procedures.
