85-2009-59　Carfilzomib 10mg　CAS No:868540-17-4　163014

特徴

• Carfilzomib is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
• Synonyms:(αS)-α-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]-L-phenylalaninamide; (αS)-α-[(4-Morpholinylacetyl)amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]-L-phenylalaninamide; PR 171
• Molecular Formula:C40H57N5O7
• Molecular Weight:719.91
• Purity:≥99% (HPLC and TLC)
• Appearance:Supplied as a white to off-white solid
• Melting Point:204-210°C
• Solubility:Soluble in DMSO at 80mg/ml; soluble in ethanol at 25mg/ml with warming; very poorly soluble in water; maximum solubility in plain water is estimated to be about 1-5uM; buffers, serum, or other additives may increase or decrease the aqueous solubility.
• Elemental Analysis:Calculated: %C: 66.73; %H: 7.98, %N: 9.73
• Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at -20°C. Stable for 6 months after receipt.. For maximum recovery of product, centrifuge the original vial prior to removing the cap.