85-1959-57　CD23, Soluble, Recombinant, Human (Low Affinity Immunoglobulin epsilon Fc Receptor, BLAST-2, C-type Lectin Domain Family 4 Member J, Fc-epsilon-RII, Immunoglobulin E-binding Factor, Lymphocyte IgE Receptor, FCER2, CD23A, CLEC4J, FCE2, IGEBF) 5ug　149659

特徴

• CD23, the low affinity receptor for IgE, belongs to the C-type lectin structural family and plays a role in the regulation of IgE synthesis and IgE mediated activities. It is found both as a transmembrane receptor protein and in a soluble form, which is generated by proteolytic cleavage of membrane bound CD23. The predominant soluble form of CD23 (sCD23) consists of 172aa corresponding to the extracellular domain of the full length precursor. sCD23, in addition to binding IgE, also exerts a number of IgE independent activities, such as promoting the activation and differentiation of B-cells and stimulating the release of pro-inflammatory cytokines from monocytes. Recombinant human sCD23 is a 19.2kD non-glycosylated protein containing 172aa.
• Source:Recombinant protein corresponding to human Soluble CD23, expressed in E.coli.
• Endotoxin:<0.1ng/ug (1EU/ug)
• AA Sequence:MELQVSSGFV CNTCPEKWIN FQRKCYYFGK GTKQWVHARY ACDDMEGQLV SIHSPEEQDF LTKHASHTGS WIGLRNLDLK GEFIWVDGSH VDYSNWAPGE PTSRSQGEDC VMMRGSGRWN DAFCDRKLGA WVCDRLATCT PPASEGSAES MGPDSRPDPD GRLPTPSAPL HS
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.