NAALADase-2 (N-acetylated-alpha-linked acid dipeptidase 2) is a Type II integral membrane protein. This zinc metallopeptidase is also known as glutamate carboxypeptidase III (1). It is a member of the transferrin receptor family of proteins and is structurally related to the Prostate Specific Membrane Antigen (PSMA), also known as glutamate carboxypeptidase II and NAALADase-1 (2, 3). Like PSMA, NAALADase-2 cleaves N-acetyl-Asp-Glu to release free glutamate (1). However, the two enzymes differ in their expression patterns (3). NAALADase2 is most highly expressed in testis and the pituitary gland, while PSMA expression is greatest in the nervous system, prostate, kidney, and small intestine.
Recombinant protein fragment of Human NAALAD2 with N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G) fusion tag.
Source:Recombinant protein, from human NAALADase-2, E. coli-derived.
Molecular Weight:~24kD
Concentration:~0.5mg/ml
Purity:≥80% (SDS-PAGE) Purified by immobilized metal affinity chromatography (IMAC)
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Source Antigen：Recombinant, E. coli
Grade：Highly Purified
Purity：≥80% (SDS-PAGE) Purified by immobilized metal affinity chromatography (IMAC)
