This family of serine proteases consists of furin and proprotein convertases encoded by PCSK genes. They are important in a variety of processes. Furin has an essential role in embryogenesis and homeostasis and is implicated in various pathologies such as cancer, neurodegenerative diseases and anthrax. Mutations in the PC1/PCSK1 gene are associated with obesity and impaired prohormone processing.
Sample Type:Cell culture supernates
Intended Use:This BioAssay™ DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant mouse Proprotein Convertase 9 (PCSK9). DuoSets are designed for the analysis of cell culture supernates.
Range:~31.2-2000pg/ml
Specificity:This DuoSet recognizes 60kD, 53kD, and LDL R complexed recombinant mouse PCSK9.
Storage and Stability:Store other components at 4°C. Stable for 6 months For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.