85-1793-13　TCS ERK 11e (Potent and Selective ERK2 Inhibitor, 4-[2-[(2-Chloro-4-fluorophenyl)amin­o]-5-methyl-4-pyrimidinyl]-N-[(1S)-1-(3-chlorophen­yl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide) 10mg　CAS No:896720-20-0　145695

特徴

• Potent and selective extracellular signal-related kinase 2 (ERK2) inhibitor (Ki values are <2, 395, 540 and 852nm for ERK2, GSK-3, Aurora Kinase A and Cdk2 respectively). Potently blocks proliferation of HT29 cells (IC50 = 48nm). Orally bioavailable.
• Sequence:C24H20Cl2FN5O2
• Solubility:DMSO (~100mM), Ethanol (~25mM)
• Molecular Weight:~500.35
• Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

仕様

• Size：10mg
• Grade：Highly Purified
• Purity：~98% (HPLC)
• Form：Supplied as a off-white solid.
• Molecular Formula：C24H20Cl2FN5O2
• Molecular Weight Non Ab：500.35
• EU Commodity Code：38220090
• この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
• 製品の仕様は予告なく変更になる場合がございます。最新仕様はメーカーホームページをご確認ください。
• CAS No ：896720-20-0

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