85-1792-93　KC7F2 (N,N'-(Dithiodi-2,1-ethanediyl)bis[2, 5-dichlorobenzenesulfonamide) 10mg　CAS No:927822-86-4　145680

特徴

• Inhibitor of HIF-1alpha. Thought to act via down-regulation of HIF-1alpha protein synthesis; reduces phosphorylation of eIF4E binding protein 1 (4EBP1) and p70 S6K in hypoxic conditions. Also blocks hypoxia-induced HIF-1alpha accumulation in a range of human cancer cell lines. Inhibits the expression of HIF target genes, such as carbonic anhydrase IX and MMP2.
• Sequence:C16H16Cl4N2O4S4
• Solubility:DMSO (~100mM)
• Molecular Weight:~570.38
• Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

仕様

• Size：10mg
• Grade：Highly Purified
• Purity：~98% (HPLC)
• Form：Supplied as a white solid.
• Molecular Formula：C16H16Cl4N2O4S4
• Molecular Weight Non Ab：570.38
• EU Commodity Code：38220090
• この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
• 製品の仕様は予告なく変更になる場合がございます。最新仕様はメーカーホームページをご確認ください。
• CAS No ：927822-86-4

• 【試薬に関するお問合せ】
• アズワン株式会社 試薬・プロセス材料グループ
• TEL：06-6447-8641
• FAX：06-6447-8642
• E-mail：[email protected]