85-1792-86 Fumitremorgin C (5aS,12S,14aS)-1,2,3,5a,6,11,12,14a-Octahydro-9-methoxy-12-(2-methyl-1-propen-1-yl)-5H,14H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione) 250ug CAS No:118974-02-0 145674
Inhibitor of BCRP-mediated multidrug resistance. Chemosensitizing agent; selectively reverses BCRP-mediated multidrug resistance to mitoxantrone, doxorubicin and topotecan in transfected MCF-7 cells. Does not reverse resistance in P-gp- or MRP-positive cells.
Sequence:C22H25N3O3
Solubility:DMSO (~10mM)
Molecular Weight:~379.45
Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.