85-1792-81　CZC 24832 (5-(2-Amino-8-fluoro[1,2,4]triazolo[ 1,5-a]pyridin-6-yl)-N-(1,1-dimethylethyl)-3-pyridi nesulfonamide) 10mg　145670

特徴

• Selective inhibitor of PI 3-Kinase gamma (IC50 = 1.0um in a PI 3-Kgamma-dependent fMLP-induced neutrophil migration assay). Exhibits limited off-target effects in kinome profiling of 154 identified lipid and protein kinases and 922 other proteins. Orally effective in a rodent model of inflammatory disease.
• Sequence:C15H17FN6O2S
• Solubility:DMSO (~100mM)
• Molecular Weight:~364.4
• Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

仕様

• Size：10mg
• Grade：Highly Purified
• Purity：~98% (HPLC)
• Form：Supplied as an off-white solid.
• Molecular Formula：C15H17FN6O2S
• Molecular Weight Non Ab：364.4
• EU Commodity Code：38220090
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