85-1791-63　Neurotrophin-3 BioAssay™ ELISA Kit, Rat 96Tests　143992

特徴

• Sandwich ELISA quantitative detection kit for Rat Neurotrophin-3 in cell culture supernates and serum.
• Neurotrophin-3 (NT-3) is a new member of the nerve growth factor gene family, which plays an important role in the development and maintenance of the vertebrate nervous system.1 NT-3 and its receptor, called neurotrophic tyrosine kinase receptor type 3 (Ntrk3; also called TrkC), are expressed early and throughout embryogenesis.2 NT-3 is one of five neurotrophin growth factors which shape the development of the nervous system by regulating neuronal survival and differentiation.3 NT-3 may be one of the central nervous system-derived factors that mediate neural crest (NC) cell proliferation in vivo.4 NT-3 has been mapped to human chromosome 12p and mouse chromosome 6.1
• Assay Range:15.6pg/ml-1000pg/ml
• Sensitivity:< 2 pg/ml
• Crossreactivity:There is cross-reactivates with NT-4 <2.5%, and no detectable cross-reactivity with any other cytokine.
• Uniprot ID:P18280
• Entrez Gene ID:81737
• Kit Components:96-well plate pre-coated with anti-Neurotrophin-3, RatLyophilized recombinant Neurotrophin-3, Rat standard, 10ng/tube, 2EaUSB Cat No Kit Component143696 Avidin-Biotin-Peroxidase Complex (ABC), 130ul (1:100 dilution)143697 Sample diluent buffer, 30ml143698 Antibody diluent buffer, 12ml143699 ABC diluent buffer, 12ml143700 TMB color developing agent, 10ml143701 TMB stop solution, 10ml
• Storage and Handling:Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles.