Sandwich ELISA quantitative detection kit for Mouse IL-27 p28 in cell culture supernates. serum and plasma (heparin, EDTA).
Interleukin-27 (IL-27) is a heterodimeric cytokine belonging to the IL-12 family that is composed of two subunits; Epstein-Barr virus (EBV)-induced gene 3 (EBI3) (also known as IL-27B) and IL27-p28 (known as IL-30). IL-27 is produced by antigen-presenting cells. By genomic sequence analysis, the IL27 p28 gene was mapped to chromosome 16p11. L-27 plays an important function in regulating the activity of B- and T-lymphocytes. The effects of IL-27 are eliciting by its interaction with a specific cell-surface receptor complex composed of two proteins known as IL27R and gp130.
Assay Range:15.6pg/ml-1000pg/ml
Sensitivity:< 10 pg/ml
Crossreactivity:There is no detectable cross-reactivity with other relevant proteins.