Sandwich ELISA quantitative detection kit for Rat IL-18 in cell culture supernates, serum and plasma (heparin, EDTA).
Interleukin (IL)-18, also called Interferon-gamma-inducing factor (IGIF), augments natural killer (NK) activity in spleen cells. The gene encodes a precursor protein of 192 amino acids and a mature protein of 157 amino acids.1 IL-18 is a recently discovered cytokine that modulates both T helper type 1 (Th1) and Th2 responses.2 IL-18 is a potent proinflammatory cytokine with potential atherogenic properties. It is highly expressed in the atherosclerotic plaques compared with control normal arteries and is localized mainly in plaque macrophages.3
Assay Range:15.6pg/ml-1000pg/ml
Sensitivity:< 1 pg/ml
Crossreactivity:There is no detectable cross-reactivity with other relevant proteins.