85-1790-62　Interleukin-1 beta (IL-1 beta) BioAssay™ ELISA Kit, Rat 96Tests　143887

特徴

• Sandwich ELISA quantitative detection kit for Rat IL-1 beta in cell culture supernates, serum and plasma (heparin, EDTA).
• The Interleukin 1 family is a group of 11 beta trefoil cytokines.1 Interleukin-1, produced mainly by blood monocytes, mediates the panoply of host reactions collectively known as acute phase response .2 Interleukin-1beta (IL-1beta) is a potent stimulator of bone resorption, and has been implicated in the pathogenesis of high bone turnover and osteoporosis.3 IL-1beta belongs to proinflammatory cytokines, promote cancer cell adhesion and liver metastases by up-regulating the expression of vascular cell adhesion molecule-1 (VCAM-1) on hepatic sinusoidal endothelium (HSE).4
• Assay Range:31.2pg/ml-2000pg/ml
• Sensitivity:< 1 pg/ml
• Crossreactivity:There is no detectable cross-reactivity with other relevant proteins.
• Uniprot ID:Q5BKB0
• Entrez Gene ID:24494
• Kit Components:96-well plate pre-coated with anti-IL-1 beta, RatLyophilized recombinant IL-1 beta, Rat standard, 10ng/tube, 2EaUSB Cat No Kit Component143696 Avidin-Biotin-Peroxidase Complex (ABC), 130ul (1:100 dilution)143697 Sample diluent buffer, 30ml143698 Antibody diluent buffer, 12ml143699 ABC diluent buffer, 12ml143700 TMB color developing agent, 10ml143701 TMB stop solution, 10ml
• Storage and Handling:Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles.