Sandwich ELISA quantitative detection kit for Human Galectin-3/ LGALS3 in cell culture supernates, serum and plasma (heparin, EDTA).
Galectin-3(GAL3), also known as LGALS3, MAC2 or GALBP, is a member of the lectin family, of which 14 mammalian galectins have been identified. Galectin-3 is encoded by a single gene, LGALS3, located on chromosome 14, locus q21–q22. It is expressed in the nucleus, cytoplasm,mitochondrion, cell surface, and extracellular space. Studies have also shown that the expression of galectin-3 is implicated in a variety of processes associated with heart failure, including myofibroblast proliferation, fibrogenesis, tissue repair, inflammation, and Ventricular remodeling. Galectin-3 is expressed in various tissues and organs, but is significantly absent in normal hepatocytes.
Assay Range:156pg/ml-10,000pg/ml
Sensitivity:< 10 pg/ml
Crossreactivity:There is no detectable cross-reactivity with other relevant proteins.