Sandwich ELISA quantitative detection kit for Human Angiostatin K1-3 in cell culture supernates, serum and plasma.
Ang K1-3 is a single, non-glycosylated polypeptide chain containing 259 amino acids. It represents a proteolytic fragment of plasminogen containing the first three kringle structures. Ang K1-3 reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth. It displays increased inhibitory activity (ED₅₀ =70 nM) relative to kringles 1-4 (ED₅₀ = 135 nM).
Assay Range:156pg/ml-10,000pg/ml
Sensitivity:< 10 pg/ml
Crossreactivity:There is no detectable cross-reactivity with other relevant proteins.