Sandwich ELISA quantitative detection kit for Human ACE2 in cell culture supernates, serum and plasma (heparin, EDTA).
AngiotensinI-converting enzyme 2 (ACE 2) is a protein belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. By sequence similarity to a sequence in GenBank, this gene is mapped to Xp22.2. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.
Assay Range:62.5pg/ml-4000pg/ml
Sensitivity:< 10 pg/ml
Crossreactivity:There is no detectable cross-reactivity with other relevant proteins.
Uniprot ID:Q9BYF1
Entrez Gene ID:59272
Kit Components:96-well plate pre-coated with anti-ACE2, HumanLyophilized recombinant ACE2, Human standard, 10ng/tube, 2Ea