Troponin I, fast skeletal muscle, also known as TNNI2, is a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in TNNI2 cause myopathy and distal arthrogryposis type 2B.
Source:Recombinant protein corresponding to aa1-182 from human TNNI2 at N-terminal, fused to His-tag expressed in E.coli.
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size:20ug
Source Antigen:Recombinant, E. coli
Grade:Highly Purified
Purity:~90% (SDS-PAGE)
Form:Supplied as a liquid in 20mM tris-HCl buffer, pH 8.0, 2M urea, 0.2M sodium chloride, 20% glycerol.