Tropomyosin is an actin-binding protein that regulates actin mechanics. It is important, among other things, for muscle contraction. Tropomyosin, along with the troponin complex, associate with actin in muscle fibers and regulate muscle contraction by regulating the binding of myosin. In resting muscle, tropomyosin overlays the myosin binding sites on actin, with a single tropomyosin molecule spanning 7 actin subunits, and is "locked" down in this position by troponin T (tropomyosin binding troponin) and troponin I (inhibitory troponin).
Source:Tropomyosin, from human cardiac tissue.
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size:100ug
Source Antigen:Human cardiac tissue
Grade:Highly Purified
Purity:~95% (SDS-PAGE)
Form:Supplied as a liquid in 10mM Tris-HCl, pH 7.4, 50mM sodium chloride, 5mM beta-mercaptoethanol, 1mM EDTA.