Protein phosphatase 1 regulatory subunit 11, also known as PPP1R11, is a 126 amino acid protein that is expressed in a variety of both adult and fetal tissues. PPP1R11 functions as an inhibitor of PP1 (protein phosphatase 1), specifically exhibiting a sensitivity toward the metal-independent and metal-dependent forms of PP1. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus.
Source:Recombinant protein corresponding to human PPP1R11, fused to His-tag at N-terminal expressed in E.coli.
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：50ug
Source Antigen：Recombinant, E.coli
Grade：Highly Purified
Purity：~90% (SDS-PAGE)
Form：Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 0.2M NaCl, 20% glycerol, 1mM DTT.
