POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging. POLE3 has been shown to interact with SMARCA5.
Source:Recombinant protein corresponding to human POLE3, fused to His-tag at N-terminal expressed in E.coli.
Enzyme Activity:Not determined. This product is recommended for use in applications that do not require a catalytically active form of the protein.
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size:100ug
Source Antigen:Recombinant, E.coli
Grade:Highly Purified
Purity:~90% (SDS-PAGE)
Form:Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 0.2M NaCl, 20% glycerol, 1mM DTT.