NSL1 is a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome- associated structures that attach to microtubules and mediate chromosome movements during cell division. The protein is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene.
Source:Recombinant protein corresponding to human NSL1, fused to His-tag at N-terminal expressed in E.coli.
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size:100ug
Source Antigen:Recombinant, E.coli
Grade:Purified
Purity:~85% (SDS-PAGE)
Form:Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0,10% glycerol 0.4M urea.