85-1780-76　C-646, HAT Inhibitor (4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1Hpyrazol- 1-yl]benzoic acid) 5mg　CAS No:328968-36-1　136762

特徴

• Potent and selective inhibitor of the histone acetyl transferase p300/CBP (Ki=400 nM ). Induces apoptosis in prostate cancer cells. Enhances fear extinction memory and synaptic plasticity in mice. Promotes tau deacetylation reducing levels of pathogenic p-tau. Cell permeable.
• Solubility:DMSO (~10mg/ml)
• Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

仕様

• Size：5mg
• Source Antigen：Synthetic
• Grade：Highly Purified
• Purity：~98% (TLC)
• Form：Supplied as a lyophilized powder in PBS. Reconstitute with sterile dH20.
• Molecular Formula：C24H19N3O6
• Molecular Weight Non Ab：445.4
• EU Commodity Code：38220090
• この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
• 製品の仕様は予告なく変更になる場合がございます。最新仕様はメーカーホームページをご確認ください。
• CAS No ：328968-36-1

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