85-1779-37　WY-14643 50mg　CAS No:50892-23-4　045394

特徴

• Potent peroxisome proliferator-activated receptor (PPARalpha) activator. Activates also PPARgamma but not PPARdelta. Potent anti-hypercholesterolemic agent. Hypolipidemic compound. Lipogenesis inducer. Tumor promoter. Causes increased cell proliferation and decreased apoptosis. Anti-inflammatory. Inhibits NF-kappaB transcriptional activity and decreases the inflammatory response by reducing the production of inflammatory cytokines (TNF-alpha, IL1beta). Reduces oxidative stress. Increases fatty acid oxidation. Directly affects insulin signaling. Increases glucose uptake.
• Synonyms:Pirinixic acid; NSC 310038; BRN 0759945; ((4-Chloro-6-((2,3-dimethylphenyl)amino)-2-pyrimidinyl)thio) acetic acid
• Molecular Weight:323.8
• Molecular Formula:C14H14ClN3O2S
• Solubility:Ethanol, DMSO, dimethyl formamide or PBS (pH 7.2).
• Appearance:Supplied as an off-white solid.
• Purity:≥98%
• Storage and Stability:Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.