85-1778-66　Sclerotiorin 500ug　045275

特徴

• Antibiotic. Antibacterial. Weak antagonist of human endothelin receptor A (ETA) and B (ETB). Cholesteryl ester transfer protein (CETP) activity inhibitor. Grb2-Shc binding inhibitor. Potent aldose reductase inhibitor. Potent reversible, non-competitive soybean lipoxygenase-1 (LOX-1) inhibitor. Antioxidant. Free radical scavenger. Antifungal.
• Synonyms:(S-(R*,R*-(E,E)))-Sclerotiorin, 7-(acetyloxy)-5-chloro-3-[(1E,3E,5S)-3,5-dimethyl-1,3-heptadien-1-yl]-7-methyl-6H-2-benzopyran-6,8(7H)-dione
• Source:Fungus Penicillium sp.
• Molecular Formula:C21H23ClO5
• Molecular Weight:390.9
• Method for Determining Identity:Proton NMR
• Appearance:Supplied as a yellow solid.
• Purity:≥97% (HPLC)
• Solubility:DMSO, ethanol or DMF. Sparingly soluble in aqueous buffers.
• Solubility in Aqueous Buffers:Dissolve in DMF and then dilute with the aqueous buffer of choice. Sclerotiorin has a solubility of ~0.3mg/ml in a 1:2 solution of DMF:PBS (pH 7.2) using this method. We do not recommend storing the aqueous solution for more than one day.
• Storage and Stability:Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.