Cell permeable smoothened (Smo) agonist. Shown to induce Sonic hedgehog (Shh) pathway activation and counteracts cyclopamine inhibition of Smo. Acts as an activator of Smo at low concentrations and as an inhibitor of Smo at very high concentrations.
Solubility:DMSO, sparingly soluble in water (acidification with HCl increases water solubility).
Method for Determining Identity:Proton NMR
Appearance:Supplied as an off-white to light yellow powder.
Purity:≥98% (NMR)
Storage and Stability:Store at -20°C. Protect from light. Store solutions at -20°C in the dark. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
仕様
Size:1mg
Grade:Highly Purified
Purity:≥98% (NMR)
Form:Supplied as an off-white to light yellow powder.