85-1778-41　Rosiglitazone maleate (BRL 49653, HSDB 7555, TDZ 01, Rosiglitazone XR, Avandia, PPAR Agonist X, PPARg Agonist IX) 25mg　045262

特徴

• Same activities as rosaglitazone but different formulation. Antidiabetic, hypoglycemic agent. Potent and selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist. Potent insulin sensitizing agent binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. Ameliorates insulin resistance. Improves blood pressure and vascular function. Enhances proliferation of endogenous neural progenitor cells (NPCs). Anti-inflammatory compound. Has controversial therapeutic effects on the cardiovascular system. Promotes adipocyte differentiation of mesenchymal stem cells (MSCs).
• Alternative Names:BRL 49653C; Rosiglitazone XR; Avandia
• Molecular Formula:C18H19N3O3S . C4H4O4
• Solubility:Soluble in ethanol or buffered aqueous solutions with pH 2.3
• Molecular Weight:~357.4, 116.1
• Method for Determining Identity:Proton NMR and Infrared Spectroscopy
• Appearance:Supplied as a white to off-white powder.
• Purity:≥98% (NMR)
• Storage and Stability:Store at 4°C. Stable for 12 months after receipt, when stored at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.