Resistin (FIZZ3; ADSF; Adipose tissue-specific secretory factor) is a 12.5kD cysteine-rich adipocytokine. In rodents, increased resistin-levels impair insulin action, while genetic ablation or down-regulation of the resistin gene improves insulin sensitivity. In humans most reports identified inflammatory cells and bone marrow-derived cells as the main source of resistin, indicating a role in inflammatory responses. Plasma resistin levels were shown to be associated with C-reactive protein (CRP), inflammatory bowel disease, Crohn's disease, atherosclerosis and acute pancreatitis. Atherosclerosis and obesity are increasingly viewed as chronic inflammatory conditions. Circulating resistin levels were reported to be increased in obesity and diabetes.
Storage and Stability:Short-term Storage: +4°CLong-term Storage: +4°C
仕様
Size：96Tests
Source Antigen：Human
Specificity：Detects human resistin. Does not cross-react with mouse resistin, rat resistin, human RELM-beta, mouse RELM-alpha, mouse RELM-beta, rat RELM-alpha, human leptin or human adiponectin.
