Anticancer compound. Chemopreventive. Shows anti-metastatic activity in prostate cancer cells through enhancement of cell-cell adhesion. Anti-invasive compound. Glycogen synthase kinase-3beta (GSK-3 beta) inhibitor.
Synonyms:PMH; 5(4-Hydroxybenzylidene)hydantoin
Source:Isolated from an unidentifed marine sponge.
Molecular Weight:204.2
Molecular Formula:C10H8N2O3
Method for Determining Identity:Proton NMR
Solubility:Ethanol or DMSO
Appearance:Supplied as a greenish solid.
Purity:≥97% (HPLC)
Storage and Stability:Store short term at 4°C. Keep cool and dry, and protect from light. For long term storage, store solutions at -20°C in the dark. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
