Periostin was originally isolated as an osteoblast-specific factor that functions as a cell adhesion molecule for pre-osteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both transforming growth factor beta1 (TGF-beta1) and bone morphogenetic protein 2 (BMP-2). Abnormal expression of periostin is also linked to angiogenesis and metastasis in epithelial tumors.
The Periostin Matched Pair Detection Set, BioAssay™ (Osteoblast-specific Factor 2, OSF-2, Postn) contains key reagents required to develop sandwich ELISA to measure human Periostin using serum, plasma and cell culture supernatant.
Detection Range:78-5000pg/ml
Sensitivity:30pg/ml
Kit Components:045140A: Standard Protein (Lyophilized), 1x1vial045140B: Coating Antibody (1mg/ml), 1x120ul045140C: Detection Antibody (Biotin) (0.1mg/ml), 1x60ul045140D: Streptavidin (HRP) (Lyophilized), 1x10ug
Contains sufficient materials to run ELISAs on 5x96-well plates
Storage and Stability:Store all components at -20°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
