85-1777-57　PD 184,352 (2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide, CI-1040) 5mg　045129

特徴

• MEK (MAPKK) inhibitor. Potent and selective MAPK (ERK kinase 1; MEK1) activation inhibitor (IC50 = 300 nM in vitro, IC50 = 2 nM in vivo). Suppresses activation of MAPK but does not block its activity. Antiproliferative. Causes cell-cycle arrest in G1 phase. Tumor suppressor. Apoptosis inducer.
• Synonyms:2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide; CI-1040
• Molecular Formula:C17H14ClF2IN2O2
• Molecular Weight:478.7
• Solubility:DMSO
• Method for Determining Identity:Proton NMR
• Appearance:White to off-white solid.
• Purity:≥95% (HPLC, NMR)
• Storage and Stability:Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

仕様

• Size：5mg
• Grade：Highly Purified
• Purity：≥95% (HPLC, NMR)
• Form：White to off-white solid.
• Molecular Formula：C17H14ClF2IN2O2
• Molecular Weight Non Ab：478.7
• EU Commodity Code：38220090
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