Omentin (Intelectin-1) is highly expressed in omental adipose tissue, small intestine and various other tissues. Omentin has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. It increases AKT phosphorylation in the absence and presence of insulin. It was suggested to play a role in the defense system against microorganisms by recognizing carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues.
Sequence:Human omentin (aa17-313) is fused at the N-terminus to a FLAG®-tag, expressed in CHO cells.
Molecular Weight:~38kD
Biological Activity:Enhances glucose transport mediated by insulin.
Endotoxin:<0.1EU/ug (LAL test; Lonza).
Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size:10ug
Source Antigen:Recombinant, Human, CHO cells
Grade:Highly Purified
Purity:≥95% (SDS-PAGE)
Form:Supplied as a lyophilized powder in PBS. Reconstitute with 100ul sterile ddH2O.