85-1777-15　Muristerone A 1mg　045051

特徴

• Muristerone A is a potent member of the ecdysteroid family. Ecdysone receptor (EcR) agonist. An analog of ecdysone with similar properties to Ponasterone A. Inducer of ecdysone-inducible gene expression systems in mammalian cells and transgenic animals.
• Induces apoptosis in cells transfected with wild-type Bax. Induces expression of beta-galactosidase. Stimulates Bcl-XL mRNA transcription and inhibits TRAIL- and hFasL-induced apoptosis in RKO cells. Insect steroid hormone involved in regulating metamorphosis, causing a response to G2 cell cycle arrest. Major molting hormone in some insects. Has protective effects in plants.
• Source:Ipomoea hederacea seeds
• Synonyms:2β,3β,5β,11α,14α,20R,22R-Heptahydroxycholest-7-en-6-one
• Molecular Weight:496.6
• Molecular Formula:C27H44O8
• Method for Determining Identity:Proton NMR
• Appearance:Supplied as a white to off-white solid.
• Purity:≥95% (HPLC)
• Solubility:Soluble in acetic acid, ethanol, methanol or DMSO. Insoluble in water.
• Usage:To prepare a 1mM stock solution (1.1mM) in 100% ethanol: Add 2ml of 100% ethanol to 1mg muristerone A (2umol). Gently mix to dissolve the product (5 to 10min.). Do not heat solution to dissolve the product. Store the 1mM stock solution at 4°C or at -20°C.
• Storage and Stability:Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.