85-1776-71　Lactacystin 500ug　CAS No:133343-34-7　044983

特徴

• Induces neuritogenesis. Potent and selective irreversible proteasome inhibitor. Specifically inhibits 20S proteasome (MCP; multicatalytic complex). Blocks proteasome activity by targeting the catalytic beta-subunit. Apoptosis inducer. Anticancer compound. Upregulates HSP70 and HSP22. Induces differentiation and inhibits cell cycle progression in several tumor cell lines. Inhibits NF-kappaB activation by inhibiting IkappaB degradation. Cathepsin A inhibitor. gamma-Secretase activity inhibitor. Anti-adipogenic.
• Source:Streptomyces lactacystinnaeus strain OM-6519
• Molecular Weight:376.4
• Molecular Formula:C15H24N2O7S
• Solubility:Water, methanol, ethanol, DMSO, pyridine, acetonitrile or dimethyl formamide. Insoluble in hexane, benzene, chloroform or ethyl acetate.
• Appearance:Supplied as a white to off-white solid.
• Purity:≥98% (HPLC)
• Storage and Stability:Store at -20°C. Caution: Light-sensitive. For maximum recovery of product, centrifuge the original vial prior to removing the cap.