85-1776-43 Irisin, Recombinant (E.coli) (Fibronectin Type III Domain-containing Protein 5, Fibronectin Type III Repeat-containing Protein 2, FNDC5) 10ug 044958
85-1776-43 Irisin, Recombinant (E.coli) (Fibronectin Type III Domain-containing Protein 5, Fibronectin Type III Repeat-containing Protein 2, FNDC5) 10ug 044958
Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin promotes brown adipocyte recruitment in white fat and improves systemic metabolism by increasing energy expenditure. Irisin is cleaved from the type I membrane protein FNDC5.
Sequence:Irisin (human, aa16-127/mouse, aa29-140) is untagged. Irisin has 100% identity between mouse, rat, monkey and human.
Molecular Weight:~12kD
Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.