IL-37 (IL-1F7; IL-1H4) belongs to the IL-1 family of proteins. It binds to the interleukin-18 receptor (IL-18R) but not to the IL-1 receptor. It plays an important role as a link between innate and adaptive immunity. IL-37 is a new player in inflammatory and immune responses, mediated by the IL-18/IL-18R axis. It was shown to inhibit tumor growth.
Sequence:Human IL-37 (aa 46-218) is fused at the C-terminus to a His-tag.
Storage and Stability:Short-term Storage: +4°CLong-term Storage: -20°CStable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
仕様
Size：10ug
Source Antigen：Recombinant, Human, E. coli
Grade：Highly Purified
Purity：>95% (SDS-PAGE)
Form：Supplied as a lyophilized powder from a 0.2um-filtered solution in 50mM TRIS-Cl, pH 8.2, 150mM NaCl.
