IL-1RI is the receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappaB. Signaling involves formation of a ternary complex containing IL1RAP, leading the activation of TOLLIP, MYD88, and IRAK1 or IRAK2.
Biological Activity:Blocks IL-1 beta activity.
Sequence:Human IL-1RI (interleukin-1 receptor type I) (aa 21-336) is fused at the C-terminus to the Fc portion of human IgG1.
Storage and Stability:Short-term Storage: +4°CLong-term Storage: -20°CStable for at least 6 months after receipt when stored at -20°C.
仕様
Size：50ug
Source Antigen：Recombinant, Human, HEK 293 cells
Grade：Highly Purified
Purity：>95% (SDS-PAGE)
Form：Supplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2.
