85-1776-06　IBMX (3-Isobutyl 1-methylxanthine, NSC 165960, SC2964, EINECS 249-259-3) 1g　CAS No:28822-58-4　044890

特徴

• Cell permeable, competitive, non-specific cAMP and cGMP phosphodiesterase inhibitor. Increases cAMP levels that activate PKA, leading to decreased proliferation, increased differentiation and induction of apoptosis. Enhances differentiation of 3T3-L1 cells. Non-selective adenosine receptor antagonist. Inhibits Ca2+ ion channels. Activates TNF-alpha. Adipogenic. Activates leukotriene synthesis. Reduces inflammation and innate immunity.
• IC50 values are 13, 18, 19, 32 and 50uM for PDE4, PDE3, PDE1, PDE5 and PDE2 respectively
• Solubility:DMSO, Dichloromethane, Ether, Ethyl acetate, Methanol and ethanol. Insoluble in water.
• Storage and Stability:Short-term Storage: +4°CLong-term Storage: -20°CStable for at least 2 years after receipt when stored at -20°C.

仕様

• Size：1g
• Grade：Highly Purified
• Purity：≥99% (HPLC)
• Form：Supplied as a white solid.
• Molecular Formula：C10H14N4O2
• Molecular Weight Non Ab：222.3
• EU Commodity Code：38220090
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• 製品の仕様は予告なく変更になる場合がございます。最新仕様はメーカーホームページをご確認ください。
• CAS No ：28822-58-4

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