85-1776-03　Hyperforin DCHA 500ug　CAS No:238074-03-8　044889

特徴

• Key constituent of St. John's wort. Shows properties of potential pharmacological interest, including anti-bacterial, anti-malarial, anti-inflammatory, anti-cancer and anti-angiogenic effects. Anti-depressant and anxiolytic compound. Specific activator of TRPC6 channels. Inhibits the re-uptake of neurotransmitters in synapses (serotonin, norepinephrine, dopamine, GABA, glutamate). Activator of the pregnane X receptor (PXR). Regulates expression of the cytochrome P450 CYP3A4 and CYP2C9 and hepatic drugs metabolism. Potential anti-Alzheimer compound. Potent SIRT1 (sirtuin 1) and SIRT2 (sirtuin 2) inhibitor.
• Synonyms:(1R,5R,6R,7S)-2-Hydroxy-6-methyl-1,3,7-tris(3-methylbut-2-enyl)-6-(4-methylpent-3-enyl)-5-(2-methylpropanoyl)bicyclo[3.3.1]non-2-ene-4,9-dione . DCHA
• Source:Isolated from St. John's wort (Hypericum perforatum)
• Molecular Weight:718.1
• Molecular Formula:C35H51O4•C12H24N
• Solubility:100% ethanol, methanol or DMSO.
• Appearance:Supplied as a white to off-white solid.
• Purity:≥97% (HPLC)
• Note:The DCHA salt stabilizes hyperforin which normally has only a short shelf life.
• Storage and Stability:Store at -20°C under inert atmosphere. Protect from light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.