85-1775-88　GYY 4137 10mg　CAS No:106740-09-4　044875

特徴

• Water-soluble, slow-releasing hydrogen sulfide (H2S) donor. Exhibits vasodilator and antihypertensive activity. Anti-inflammatory. Inhibits LPS-induced release of proinflammatory mediators (IL-1beta, IL-6, TNF-alpha, nitric oxide (NO) and PGE2) and increases the synthesis of the anti-inflammatory chemokine IL-10 through NF-kappaB, ATF-2 and HSP27 dependent pathways. Causes stomatal opening and reduces nitric oxide accumulation in plants. Oxidative stress-induced cell death inhibitor. Shows novel anti-cancer effects in vitro and in vivo. Anti-thrombotic via p-selectin dependent mechanism.
• Synonyms:4-Methoxyphenyl(morpholino)phosphinodithioate morpholinium salt
• Molecular Weight:375.5
• Molecular Formula:C11H16NO2PS2•C4H9NO
• Solubility:DMSO or water
• Appearance:Supplied as a white solid.
• Purity:≥95% (NMR)
• Method for Determining Identity:Proton NMR
• Storage and Stability:May be stored at 4°C for short-term only. Protect from light and moisture. Stable for 12 months after receipt when stored at -20°C. Store solutions at -20°C in the dark. For maximum recovery of product, centrifuge the original vial prior to removing the cap.