FGF-21 (Fibroblast growth factor 21) stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of betaKlotho.
Biological Activity:Activates ERK and FRS2alpha phosphorylation in bKlotho expressing cells.
Sequence:Human FGF-21 (aa 1-209) is fused at the C-terminus to the Fc portion of human IgG1.
Storage and Stability:Short-term Storage: +4°CLong-term Storage: -20°CWorking aliquots are stable for up to 3 months when stored at -20°C.
仕様
Size：10ug
Source Antigen：Recombinant, Human, HEK 293 cells
Grade：Highly Purified
Purity：>95% (SDS-PAGE)
Form：Supplied as a liquid from a 0.2um-filtered solution in PBS, pH 7.2.
