FasL is a cytokine that binds to Fas/TNFRSF6, a receptor that transduces the apoptotic signal into cells. FasL is involved in cytotoxic T cell mediated apoptosis and in T cell development.
Binds human FasL with an ED50 of <5ng/ml. Binds mouse FasL.
Sequence:The Fc portion of human IgG1 is fused to the C-terminus of human Fas (aa 26-170).
Biological Activity:Blocks the binding of FasL to Fas.
Molecular Weight:~47kD (SDS-PAGE).
Endotoxin:<0.01EU/ug (LAL test; Lonza).
Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：50ug
Source Antigen：Recombinant, Human, HEK 293 cells
Grade：Highly Purified
Purity：≥95% (SDS-PAGE)
Form：Supplied as a lyophilized powder in PBS. No preservative added. Reconstitute with 50ul sterile ddH2O.
