CTRP5 (C1qTNF-related protein 5; C1QTNF5) belongs to a highly conserved family of adiponectin paralogs. CTRP5 mediates activation of AMP-activated protein kinase (AMPK) in muscle and liver cells, thereby regulating glucose and lipid metabolism. Serum levels of CTRP5 are significantly higher in obese/diabetic animal models compared to normal controls. Furthermore, CTRP5 may be a putative biomarker for mitochondrial dysfunction. Defects in C1QTNF5 are a cause of late-onset retinal degeneration (LORD).
Recombinant protein corresponding to full-length human CTRP5 (aa16-243), fused to His-tag at N-terminal, expressed in E. coli.
Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 6 months after receipt at -20°C. Reconstitute, aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 3 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：10ug
Source Antigen：Recombinant, Human, E. coli
Grade：Highly Purified
Purity：≥90% (SDS-PAGE)
Form：Supplied as a lyophilized powder from a 0.2um-filtered solution in 55mM TRIS-Cl, pH 8.2, 150mM sodium chloride. Reconstitute with sterile dH2O
